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Two dimensional gel electrophoresis comparison of bone marrow fluid from G-CSF treated wildtype and em SFK /em ?/? mice revealed a significant decrease in global protein expression in em SFK /em ?/? mice compared to wildtype, suggestive of enhanced proteolysis

Two dimensional gel electrophoresis comparison of bone marrow fluid from G-CSF treated wildtype and em SFK /em ?/? mice revealed a significant decrease in global…

Similarly, transient depletion of OPTN using two different siRNA targeting OPTN (siOPTN #1 and siOPTN #2) for 48 hours in HeLa cells stably expressing CFP-htt ex1 Q103 led to an increased number of cells containing aggregates as well as insoluble CFP-htt ex1 Q103 compared to control cells expressing OPTN (Fig

Similarly, transient depletion of OPTN using two different siRNA targeting OPTN (siOPTN #1 and siOPTN #2) for 48 hours in HeLa cells stably expressing CFP-htt…